Creation of a dedicated research area in the new maternity hospital of "Cochin Port - Royal"

Equip a laboratory with biological samples of the newborn baby and its mother in order to centralize them at the PremUp biological bank.

Context

The construction of the new Maternity Hospital of "Cochin Port-Royal", to be completed in 2010, will represent an impressive tool dedicated to perinatality, an area long neglected and yet so important in terms of public health.
Through this project, the activities of the maternity hospitals of Port-Royal, Baudelocque and St-Vincent de Paul – that is, obstetrics/gynaecology, neonatology and associated biological activities will be combined in one place. This care facility will include 119 beds for maternity cases, 37 for gynaecology and 63 for neonatal cases of type III. The building will also provide space for research in perinatology, which constitutes the core of PremUp's activity.

Objectives

  • Equip, within this new maternity hospital, a technological PremUp platform (96 m2 ) for taking and processing biological samples. This would include a laboratory for cell culture and a biochemical
    laboratory, as well as the administrative seat of the Foundation (36 m2). Unit Inserm 953-UPMC (dedicated to epidemiological research in perinatal health and the health of women and children) and the Cochin-Necker Centre of Clinical Investigation) will be situated in premises adjacent to those of the Foundation. These two research units form part of the PremUp network.
  • Take and process samples of biological material from the premature newborn baby and its mother, to be transferred and centralised in the bank of biological and clinical data at Creteil. This bank will combine the collection of samples from the 3 care centres of PremUp, thus providing the network of researchers and clinicians with enough information to verify their research hypotheses on the pathologies of pregnancy and prematurity.
  • Bring the PremUp teams together on the same premises to facilitate daily interaction that will stimulate medical progress in perinatology.

Added value of PremUp

With the capacity to cater for 6.000 births per year, and numerous university hospitals represented in their research units, the PremUp network will have at its disposal, on the same premises, an exceptional range of biological, clinical and epidemiological expertise.

Projected budget

Fitting out and equipping 132 m² 400.000
Annual operating costs of 132 m2 for 10 years 160.000

Administration costs of the project
(5 % of the total amount)

 28.000
588.000

  • Prevention of respiratory sequellae in premature newborn babies: role of genetics

  • Protection of the brain of the premature newborn : clinical trials on melatonin

  • Medical imaging, a tool in early detection of cerebral lesions in the premature baby

  • Research into the capacity of stem cells to repair cerebral lesions in the premature newborn

  • The lungs of premature babies: research into new anti-inflammatory treatment

  • Infectious disease in premature newborn babies

  • The EPIPAGE 2 study